Fierce-a pre-workout complex from SAN, which is widely popular, is included in the TOP of the best.
Fierce was created primarily with the aim of increasing endurance and strength indicators, helping an athlete to lift more weights and perform exercises with greater intensity. Fierce from SAN perfectly reduces the feeling of fatigue. Let’s look at the composition of our product and describe the contribution of each component to the overall effect of the additive. A special proprietary mixture consists of five separate parts, each of which enhances the effect of other components.
Cell Hydration Matrix-the matrix of cellular hydration
Of all the components of Fierce from SAN, the most familiar for athletes, for sure, will be creatine, which is represented by various forms. A large number of studies have shown that creatine leads to increased strength and athletic performance. There are several theories that explain the mechanism of action of creatine, the most likely of which states that creatine increases the concentration of creatine phosphate in skeletal muscles, accelerating the recovery of ATP – the main energy substrate of the body.
Recently, creatine letrozole has also been shown to increase the glycogen content in muscles and accelerate the synthesis of heavy chains of myosin (muscle contractile protein) (https://englandpharmacy.co.uk/category/aromatase-inhibitors/letrozole/). Creatine increases the secretion of insulin-like growth factor. (Deldicque et al 2005)
Why does Fierce contain Creatine Malate? The fact is that malate is a key intermediary in the so-called tricarboxylic acid cycle, which provides the entire body with energy. It is the tricarboxylic acid cycle that synthesizes new ATP molecules. During prolonged aerobic activity, the body needs increased amounts of malate, which can come in the form of creatine malate.
Creatine ethyl ester is another form of creatine, which is one of the most popular at present. The main difference between creatine ethyl ester and monohydrate is that the creatine molecule is not bound to water, but to ether. Creatine monohydrate, entering the digestive tract, quickly loses a water molecule and turns into a byproduct of metabolism – creatinine, which is useless for muscles. Despite the fact that creatinine is a natural slag of the body, in bodybuilding it can represent a number of undesirable actions. Creatine, which is combined with an ether molecule, does not contain water and is not converted into creatinine. Creatine ester does not cause digestive problems.
Nitro NO-nitric oxide
One of the key factors for controlling the lumen of blood vessels, which is contained in Fierce from SAN, is nitric oxide (NO). In the body, nitric oxide is synthesized from the amino acid arginine. When nitric oxide interacts with the vessel wall, it begins to relax, as a result of which the lumen increases and blood flow increases. Skeletal muscles need large amounts of blood, which carries a lot of nutrients and oxygen, and also cleanses the muscles from metabolic products. For this reason, arginine was included in the composition of Fierce, it provides a powerful pumping after training, as well as improves muscle nutrition and accelerates their recovery. Arginine alpha-ketoglutarate, according to some data, is better absorbed in the intestine than the simple form of arginine. Arginine alpha-ketoglutarate is widely used in sports nutrition and is even used for medical purposes.
Creatine Assimilator-creatine assimilator (assimilation enhancer)
Glycocyamine and guanidinopropionic acid are added to the composition of Fierce for the reason that they have an effect similar to insulin – they lower the concentration of glucose in the blood and accelerate the transport of creatine. (Meglasson et al 1993) It is obvious that this ability is associated with increased expression of GLUT-4, the main glucose transporter (Ren 1993). In addition, glycocyamine is able to convert itself into creatine in the liver, thereby creating an additional source, in addition to creatine malate and creatine ethyl ester.
Anhydrous betaine is a powerful tool for reducing the toxic slag-homocysteine. Scientists have confirmed that betaine lowers homocysteine levels by an average of 20% from the baseline level (Olthof et al 2005). It has also been demonstrated that betaine is able to accelerate recovery after exercise and reduce muscle fatigue, due to faster utilization of lactic acid.